Development of magnetic molecularly imprinted polymers with double templates for the rapid and selective determination of carbamazepine and lamotrigine in serum

Author:

Wei Ya-qin1,Zhao Lin-lin1,You Yu-xin1,Zhao Yan-lin2,Zheng Xiao-xiao3,Du Yan1,Tang Dao-quan134ORCID

Affiliation:

1. Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, China

2. Department of Pharmacy, Suining People's Hospital Affiliated to Xuzhou Medical University, Suining 221202, China

3. Department of Pharmacy, Xuzhou Municipal Hospital Affiliated to Xuzhou Medical University, Xuzhou 221002, China

4. Department of Pharmaceutical Analysis, Xuzhou Medical University, 209 Tongshan Road, Xuzhou 221204, Jiangsu Province, China

Abstract

A dual-template magnetic molecularly imprinted polymer (Dt-MMIP) with a specific recognition capability for carbamazepine and lamotrigine was synthesized using methacrylic acid as a functional monomer, and ethylene glycol dimethylmethacrylate as a cross-linking agent.

Funder

Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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