Fabrication of a surface molecularly imprinted polymer membrane based on a single template and its application in the separation and extraction of phenytoin, phenobarbital and lamotrigine-Reference-Cited by-同舟云学术

Fabrication of a surface molecularly imprinted polymer membrane based on a single template and its application in the separation and extraction of phenytoin, phenobarbital and lamotrigine

Published:2024 Issue:12 Volume:14 Page:8353-8365
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhao Yan-lin¹,You Yu-xin²,Chen Yu-lang¹,Zhang Ying¹,Du Yan²³,Tang Dao-quan¹²^ORCID

Affiliation:

1. Department of Pharmacy, Suining People's Hospital Affiliated to Xuzhou Medical University, Suining 221202, China

2. Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou 221004, Jiangsu Province, China

3. State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, Nanjing, 210093, China

Abstract

A molecularly imprinted polymer membrane (MIPM) was prepared using PVDF as the support and phenytoin (PHT) as a single template. The results indicated that the MIPMs can be used to extract PHT, phenobarbital, and lamotrigine in different matrices.

Funder

Natural Science Foundation of Jiangsu Province

Natural Science Foundation of Xuzhou Municipality

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA00294F

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