Scale-up of N-alkylation reaction using phase-transfer catalysis with integrated separation in flow-Reference-Cited by-同舟云学术

Scale-up of N-alkylation reaction using phase-transfer catalysis with integrated separation in flow

Published:2019 Issue:2 Volume:4 Page:334-345
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Nieves-Remacha María José¹²³⁴^ORCID,Torres Myriam¹²³⁴^ORCID,Ruiz-Abad María¹²³⁴^ORCID,Rincón Juan A.¹²³⁴^ORCID,Cumming Graham R.¹²³⁴^ORCID,Garcia-Losada Pablo¹²³⁴^ORCID

Affiliation:

1. Centro de Investigación Lilly S.A.

2. Avda. de la Industria

3. 30, 28108 Alcobendas

4. Spain

Abstract

Scaling-up phase-transfer catalysis in flow.

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RE/C8RE00203G

Reference73 articles.

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4. P. Garcia-Losada , Alternative Synthetic Technologies transforming traditional synthetic activities in discovery chemistry: Impact on scale-up for GLP material supply, 38th Org. Process Res. Dev. Conference , Stockholm, Sweden , September, 2017

5. P. Garcia-Losada , Scale-Up of N-Alkylation Reaction Using Phase Transfer Catalysis in Flow, Gordon Research Conference: Organic reactions and processes , Boston, United States , June, 2018

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