A dienamine-mediated deconjugative addition/cyclization cascade of γ,γ-disubstituted enals with carboxylic acid-activated enones: a rapid access to highly functionalized γ-lactones-Reference-Cited by-同舟云学术

A dienamine-mediated deconjugative addition/cyclization cascade of γ,γ-disubstituted enals with carboxylic acid-activated enones: a rapid access to highly functionalized γ-lactones

Published:2020 Issue:3 Volume:7 Page:571-577
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Jiang Wei¹²³⁴⁵,Zhou Jia⁶⁷⁸⁹⁵,Ma Ai-Jun¹²³⁴⁵,Li Dongli¹²³⁴⁵^ORCID,Ma Yan-Yan¹²³⁴⁵,Zhao Deng-Gao¹²³⁴⁵,Hou Si-Hua⁶⁷⁸⁹⁵,Lin Jun-Bing¹⁰¹¹¹²¹³⁵,Zhang Shu-Yu¹²³⁴⁵^ORCID

Affiliation:

1. School of Biotechnology and Health Sciences

2. International Healthcare Innovation Institute

3. Wuyi University

4. Jiangmen 529020

5. China

6. Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs

7. School of Chemistry and Chemical Engineering

8. Shanghai Jiao Tong University

9. Shanghai 200240

10. Shaanxi Key Laboratory of Chemical Reaction Engineering

11. College of Chemistry and Chemical Engineering

12. Yan'an University

13. Yan'an 716000

Abstract

An aminocatalytic deconjugative addition/cyclization cascade of γ,γ-disubstituted enals with carboxylic acid-activated enones was realized, giving rise to highly functionalized γ-lactones with excellent enantioselectivities.

Funder

Recruitment Program of Global Experts

National Natural Science Foundation of China

Wuyi University

Department of Education of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/C9QO01367A

Reference88 articles.