A halogen bond-mediated highly active artificial chloride channel with high anticancer activity-Reference-Cited by-同舟云学术

A halogen bond-mediated highly active artificial chloride channel with high anticancer activity

Published:2018 Issue:17 Volume:9 Page:4044-4051
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Ren Changliang¹²^ORCID,Ding Xin¹²,Roy Arundhati¹²^ORCID,Shen Jie¹²,Zhou Shaoyuan³⁴⁵⁶,Chen Feng¹²,Yau Li Sam Fong⁷⁸⁹¹⁰^ORCID,Ren Haisheng³⁴⁵⁶^ORCID,Yang Yi Yan¹²^ORCID,Zeng Huaqiang¹²^ORCID

Affiliation:

1. Institute of Bioengineering and Nanotechnology

2. Singapore 138669

3. College of Chemical Engineering

4. Sichuan University

5. Chengdu

6. China 610065

7. NUS Environmental Research Institute

8. Department of Chemistry

9. National University of Singapore

10. Singapore 117543

Abstract

Modularly tunable monopeptidic scaffold enables rapid and combinatorial evolution of a halogen bond-mediated highly active chloride channel, exhibiting an excellent anticancer activity toward human breast cancer.

Funder

National Research Foundation Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/SC/C8SC00602D

Reference58 articles.

1. Mechanism of ion transport through the anion-selective channel of the Pseudomonas aeruginosa outer membrane.

2. Chloride Channels: Often Enigmatic, Rarely Predictable

3. Applications of Supramolecular Anion Recognition