Preparation and evaluation of celecoxib nanosuspensions for bioavailability enhancement-Reference-Cited by-同舟云学术

Preparation and evaluation of celecoxib nanosuspensions for bioavailability enhancement

Published:2017 Issue:22 Volume:7 Page:13053-13064
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

He Jiali¹²³⁴⁵,Han Yue¹²³⁴⁵,Xu Gujun¹²³⁴⁵,Yin Lifang¹²³⁴⁵,Ngandeu Neubi M.¹²³⁴⁵,Zhou Jianping¹²³⁴⁵,Ding Yang¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Natural Medicines

2. Department of Pharmaceutics

3. China Pharmaceutical University

4. Nanjing 210009

5. China

Abstract

We prepare celecoxib nanosuspensions using TPGS as stabilizer via high speed shear as a pre-treatment step, followed by HPH method; and the solidification of fresh nanosuspension was carried out by freeze-drying.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C6RA28676C

Reference55 articles.

1. Comparing various techniques to produce micro/nanoparticles for enhancing the dissolution of celecoxib containing PVP

2. Promising dissolution enhancement effect of soluplus on crystallized celecoxib obtained through antisolvent precipitation and high pressure homogenization techniques

3. Advantages of celecoxib nanosuspension formulation and transformation into tablets

4. Quality by design approach for developing chitosan-Ca-alginate microspheres for colon delivery of celecoxib-hydroxypropyl-β-cyclodextrin-PVP complex

5. Development and evaluation of novel solid nanodispersion system for oral delivery of poorly water-soluble drugs

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