Biorelevant Dissolution Method Considerations for the Appropriate Evaluation of Amorphous Solid Dispersions: are Two Stages Necessary?

Author:

Wang ZhaoxianORCID,Lou HaoORCID,Dening Tahnee J.,Hageman Michael J.ORCID

Funder

University of Kansas

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference56 articles.

1. What is the true solubility advantage for amorphous pharmaceuticals?;Hancock;Pharm Res,2000

2. The use of amorphous solid dispersions: A formulation strategy to overcome poor solubility and dissolution rate;Van Den Mooter;Drug Discov Today: Technol,2012

3. Drug-polymer-water interaction and its implication for the dissolution performance of amorphous solid dispersions;Chen;Mol Pharm,2015

4. Theoretical and experimental investigation of drug-polymer interaction and miscibility and its impact on drug supersaturation in aqueous medium;Baghel;Eur J Pharm Biopharm,2016

5. Balancing solid-state stability and dissolution performance of lumefantrine amorphous solid dispersions: the role of polymer choice and drug–polymer interactions;Hiew;Mol Pharm,2021

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