Diastereoselective synthesis of spiro[benzo[d]pyrrolo[2,1-b]thiazole-3,3′-indolines] via cycloaddition reaction of N-phenacylbenzothiazolium bromides and 3-methyleneoxindoles

Author:

Shen Guo-Liang1234,Sun Jing1234,Yan Chao-Guo1234

Affiliation:

1. College of Chemistry & Chemical Engineering

2. Yangzhou University

3. Yangzhou 225002

4. China

Abstract

The domino cycloaddition reactions of N-phenacylbenzothiazolium bromides with 3-phenacylideneoxindoles or ethyl 2-(2-oxoindolin-3-ylidene)acetates afforded spiro[benzo[d]pyrrolo[2,1-b]thiazole-3,3′-indolines] in good yields and with high diastereoselectivity.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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