Regioselective 5-exo-dig oxy-cyclization of 2-alkynylbenzamide for the synthesis of isobenzofuran-1-imines and isobenzofuran-Reference-Cited by-同舟云学术

Regioselective 5-exo-dig oxy-cyclization of 2-alkynylbenzamide for the synthesis of isobenzofuran-1-imines and isobenzofuran

Published:2018 Issue:24 Volume:16 Page:4501-4508
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wang Rui-Xiang¹²³⁴,Yuan Si-Tian¹²³⁴⁵,Liu Jin-Biao¹²³⁴^ORCID,Wu Jie⁵⁶⁷⁸⁴^ORCID,Qiu Guanyinsheng⁵⁶⁷⁸⁴^ORCID

Affiliation:

1. School of Metallurgical and Chemical Engineering

2. Jiangxi University of Science and Technology

3. Ganzhou 341000

4. China

5. College of Biological

6. Chemical Science and Engineering

7. Jiaxing University

8. Jiaxing 314001

Abstract

A TBAB-mediated regioselective radical cyclization of 2-alkynylbenzamide is described herein for the synthesis of isobenzofuran-1-imines. The reactions proceeded smoothly under mild conditions.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangxi Province

Jiangxi University of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB00779A

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