Short, enantioselective, gram-scale synthesis of (−)-zephyranthine

Author:

Zhao Yuxiang12345ORCID,Zhu Yanren12345,Ma Guolan12345,Wei Qi12345ORCID,Yang Shaoxiong12345,Zeng Xiaoyu12345ORCID,Zhang Hongbin12345ORCID,Chen Jingbo12345ORCID

Affiliation:

1. Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education

2. Yunnan Provincial Center for Research & Development of Natural Products

3. School of Chemical Science and Technology

4. Yunnan University

5. Kunming

Abstract

A reasonable synthesis design by strategically integrating functional group manipulation into the ring system construction resulted in a short, enantioselective, gram-scale total synthesis of (−)-zephyranthine.

Funder

National Natural Science Foundation of China

Yunnan Provincial Science and Technology Department

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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5. O. Hoshino , in The Alkaloids , ed. G. A. Cordell , Academic Press , San Diego , 1998 , vol. 51 , pp. 323−424

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