An organometallic structure-activity relationship study reveals the essential role of a Re(CO)3moiety in the activity against gram-positive pathogens including MRSA-Reference-Cited by-同舟云学术

An organometallic structure-activity relationship study reveals the essential role of a Re(CO)3moiety in the activity against gram-positive pathogens including MRSA

Published:2015 Issue:1 Volume:6 Page:214-224
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Patra Malay¹²³⁴⁵,Wenzel Michaela³⁶⁷⁴⁵,Prochnow Pascal³⁶⁷⁴⁵,Pierroz Vanessa⁸⁹¹⁰¹¹,Gasser Gilles⁸⁹¹⁰¹¹,Bandow Julia E.³⁶⁷⁴⁵,Metzler-Nolte Nils¹²³⁴⁵

Affiliation:

1. Lehrstuhl für Anorganische Chemie I – Bioanorganische Chemie

2. Fakultät für Chemie und Biochemie

3. Ruhr-Universität Bochum

4. Universitätsstrasse 150

5. D-44801 Bochum

6. Biologie der Mikroorganismen

7. Arbeitsgruppe Mikrobielle Antibiotikaforschung

8. Department of Chemistry

9. University of Zurich

10. CH-8057 Zurich

11. Switzerland

Abstract

A systematic structure activity relationship reveals the contribution of individual organometallic moieties to the potency of a new structural class of hetero-trimetallic antibacterial agents.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/SC/C4SC02709D

Reference55 articles.

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3. ECDC/EMEA Joint Working Group , The Bacterial Challenge, The Publications Office of the European Union, 2009, Stockholm

4. New Ways of Killing the Beast: Prospects for InorganicâOrganic Hybrid Nanomaterials as Antibacterial Agents

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