Direct synthesis of 2-substituted benzonitriles via alkylcyanation of arynes with N,N-disubstituted aminomalononitriles-Reference-Cited by-同舟云学术

Direct synthesis of 2-substituted benzonitriles via alkylcyanation of arynes with N,N-disubstituted aminomalononitriles

Published:2020 Issue:55 Volume:56 Page:7641-7644
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Bao Wen¹²³⁴,Gao Zhu-Peng¹²³⁴,Jin Da-Ping¹²³⁴,Xue Cao-Gen¹²³⁴,Liang Huan¹²³⁴,Lei Ling-Sheng¹²³⁴,Xu Xue-Tao⁵⁶⁷⁴^ORCID,Zhang Kun⁵⁶⁷⁴,Wang Shao-Hua¹²³⁴⁵^ORCID

Affiliation:

1. School of Pharmacy & State Key Laboratory of Applied Organic Chemistry

2. Lanzhou University

3. Lanzhou 730000

4. P. R. China

5. School of Biotechnology and Health Science

6. Wuyi University

7. Jiangmen 529020

Abstract

An efficient alkylcyanation of in situ generated arynes by N,N-disubstituted aminomalononitriles is described, enabling the direct synthesis of 2-substituted benzonitriles.

Funder

National Natural Science Foundation of China

Department of Education of Guangdong Province

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/D0CC01591A

Reference44 articles.

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