Palladium-catalyzed stereoselective trifluoromethylated allylic alkylation of 3-substituted oxindoles-Reference-Cited by-同舟云学术

Palladium-catalyzed stereoselective trifluoromethylated allylic alkylation of 3-substituted oxindoles

Published:2022 Issue:3 Volume:9 Page:810-815
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Li Dong¹,Zhang Shuaibo¹,Wang Bangzhong¹,Sun Wuding¹,Zhao Jinfeng²,Qu Jingping²^ORCID,Zhou Yuhan¹^ORCID

Affiliation:

1. State Key Laboratory of Fine Chemicals, Department of Pharmaceutical Sciences, School of Chemical Engineering, Dalian University of Technology, 2 Linggong Road, Dalian 116024, China

2. State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, 2 Linggong Road, Dalian 116024, China

Abstract

The palladium-catalyzed asymmetric trifluoromethylated allylic alkylation of 3-substituted oxindoles using α-(trifluoromethyl)alkenyl acetates as trifluoromethyl-containing allyl precursors was developed.

Funder

Dalian Science and Technology Innovation Fund

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D1QO01597D

Reference34 articles.

1. Small-Molecule Inhibitors of the MDM2–p53 Protein–Protein Interaction (MDM2 Inhibitors) in Clinical Trials for Cancer Treatment

2. Recent progress in enantioselective synthesis of C3-functionalized oxindoles: rare earth metals take action