Small-Molecule Inhibitors of the MDM2–p53 Protein–Protein Interaction (MDM2 Inhibitors) in Clinical Trials for Cancer Treatment-Reference-Cited by-同舟云学术

Small-Molecule Inhibitors of the MDM2–p53 Protein–Protein Interaction (MDM2 Inhibitors) in Clinical Trials for Cancer Treatment

Published:2014-11-14 Issue:3 Volume:58 Page:1038-1052
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhao Yujun¹,Aguilar Angelo¹,Bernard Denzil¹,Wang Shaomeng¹

Affiliation:

1. University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine, Pharmacology, and Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States

Funder

National Cancer Institute

Sanofi

Leukemia and Lymphoma Society

Prostate Cancer Foundation

Ascenta Therapeutics

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501092z

Reference79 articles.

1. MDM2, MDMX and p53 in oncogenesis and cancer therapy

2. Live or let die: the cell's response to p53

3. The p53 family in differentiation and tumorigenesis

4. Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

5. Awakening guardian angels: drugging the p53 pathway

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