Applying the prodrug strategy to α-phosphonocarboxylate inhibitors of Rab GGTase – synthesis and stability studies-Reference-Cited by-同舟云学术

Applying the prodrug strategy to α-phosphonocarboxylate inhibitors of Rab GGTase – synthesis and stability studies

Author:

Joachimiak Łukasz¹²³⁴,Janczewski Łukasz¹²³⁴,Ciekot Jarosław⁵⁶⁷⁸⁴,Boratyński Janusz⁵⁶⁷⁸⁴,Błażewska Katarzyna¹²³⁴

Affiliation:

1. Institute of Organic Chemistry

2. Lodz University of Technology

3. 90-924 Łódź

4. Poland

5. “Neolek” – Department of Experimental Oncology

6. Ludwik Hirszfeld Institute of Immunology and Experimental Therapy

7. Polish Academy of Sciences

8. 53-144 Wroclaw

Abstract

First prodrug-like analogs of highly ionic inhibitors of RGGT were obtained and their chemical and enzymatic stability was evaluated.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

Reference38 articles.

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