In vitro evaluation and in vivo demonstration of a biomimetic, hemocompatible, microfluidic artificial lung-Reference-Cited by-同舟云学术

In vitro evaluation and in vivo demonstration of a biomimetic, hemocompatible, microfluidic artificial lung

Published:2015 Issue:5 Volume:15 Page:1366-1375
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Kovach K. M.¹²³⁴,LaBarbera M. A.⁵⁶³⁴^ORCID,Moyer M. C.⁷⁸²³⁴,Cmolik B. L.⁹²³⁴,van Lunteren E.⁷⁸²³⁴,Sen Gupta A.¹⁰⁶³⁴,Capadona J. R.¹²³⁴¹⁰,Potkay J. A.¹²³⁴⁵^ORCID

Affiliation:

1. Advanced Platform Technology Center (APT Center)

2. Louis Stokes Cleveland VA Medical Center

3. Cleveland

4. USA

5. Department of Electrical Engineering and Computer Science

6. Case Western Reserve University

7. Pulmonary, Critical Care, and Sleep Division

8. Department of Medicine

9. Surgical Service

10. Department of Biomedical Engineering

Abstract

We describe the first microfluidic artificial lung featuring a hemocompatible surface coating and a biomimetic blood path and its application in an in vitro and in vivo model.

Funder

U.S. Department of Veterans Affairs

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2015/LC/C4LC01284D

Reference38 articles.

1. Advances in artificial lungs

2. A microfluidic respiratory assist device with high gas permeance for artificial lung applications

3. Towards microfabricated biohybrid artificial lung modules for chronic respiratory support