Aptamer-based colorimetric detection of the DNA damage marker 8-oxo-dG using cysteamine-stabilised gold nanoparticles-Reference-Cited by-同舟云学术

Aptamer-based colorimetric detection of the DNA damage marker 8-oxo-dG using cysteamine-stabilised gold nanoparticles

Published:2022 Issue:39 Volume:12 Page:25478-25486
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sakonsinsiri Chadamas¹²^ORCID,Puangmali Theerapong³^ORCID,Sreejivungsa Kaniknun¹,Koowattanasuchat Sireemas¹,Thanan Raynoo¹²,Chompoosor Apiwat⁴,Kulchat Sirinan⁵^ORCID,Sithithaworn Paiboon⁶

Affiliation:

1. Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand

2. Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen 40002, Thailand

3. Department of Physics, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand

4. Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand

5. Department of Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand

6. Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand

Abstract

A colorimetric assay based on cysteamine-stabilized AuNPs and anti-8-oxo-dG aptamers for the detection of 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxo-dG), which is a critical DNA damage marker, was developed.

Funder

Khon Kaen University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA01858F

Reference35 articles.

1. Base-excision repair of oxidative DNA damage

2. Oxidation of 7,8-Dihydro-8-oxoguanine Affords Lesions That Are Potent Sources of Replication Errors in Vivo

3. The Role of Oxidative Stress in Carcinogenesis