Recent advances in gold nanoparticle-based colorimetric aptasensors for chemical and biological analyses

Author:

Behzad Farahnaz1ORCID,Samadi Azam23ORCID,Rahimpour Elaheh24ORCID,Adabi Mahdi15ORCID,Jouyban Abolghasem26ORCID

Affiliation:

1. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran

2. Pharmaceutical Analysis Research Center & Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran

3. Biotechology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

4. Infectious & Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

5. Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, Iran

6. Faculty of Pharmacy, Near East University, PO Box 99138 Nicosia, North Cyprus, Mersin 10, Turkey

Abstract

Aptasensors are amazing among many currently formed procedures due to their excellent particularity, selectivity and responsiveness. These biosensors get more popular in combination with gold nanoparticles (AuNPs) to detect chemical and biological molecules. The response of AuNPs by changing color provides a simple explanation of outcomes. The authors review the recent developments in AuNP-based colorimetric aptasensors designed to sense different chemical and biological molecules. They summarize the procedure of AuNP-based detection and the ordinary instances of currently formed AuNP-based colorimetric procedures. Furthermore, their uses for detecting different analytes based on analyte types are given and the present challenges, overview, and positive views for forming new aptasensors are also regarded.

Funder

Tabriz University of Medical Sciences

Publisher

Future Science Ltd

Subject

Medical Laboratory Technology,Clinical Biochemistry,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Analytical Chemistry

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