Expansion of chemical space for natural products by uncommon P450 reactions-Reference-Cited by-同舟云学术

Expansion of chemical space for natural products by uncommon P450 reactions

Published:2017 Issue:9 Volume:34 Page:1061-1089
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Zhang Xingwang¹²³⁴⁵^ORCID,Li Shengying¹²³⁴⁵^ORCID

Affiliation:

1. Shandong Provincial Key Laboratory of Synthetic Biology

2. CAS Key Laboratory of Biofuels at Qingdao Institute of Bioenergy and Bioprocess Technology

3. Chinese Academy of Sciences

4. Qingdao

5. China

Abstract

This review focuses on unusual P450 reactions related to new chemistry, skeleton construction, structure re-shaping, and protein–protein interactions in natural product biosynthesis, which play significant roles in chemical space expansion for natural products.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NP/C7NP00028F

Reference194 articles.

1. Culturability and Secondary Metabolite Diversity of Extreme Microbes: Expanding Contribution of Deep Sea and Deep-Sea Vent Microbes to Natural Product Discovery

2. Discovery of microbial natural products by activation of silent biosynthetic gene clusters

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4. Natural products and plant disease resistance

5. Biosynthetic origin of natural products isolated from marine microorganism-invertebrate assemblages

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