Facile oxidative cyclization to access C2-quaternary 2-hydroxy-indolin-3-ones: synthetic studies towards matemone-Reference-Cited by-同舟云学术

Facile oxidative cyclization to access C2-quaternary 2-hydroxy-indolin-3-ones: synthetic studies towards matemone

Published:2017 Issue:20 Volume:41 Page:11503-11506
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Wen Sai-Shuai¹²³,Zhou Zhao-Fang¹²³,Xiao Jun-An⁴⁵³,Li Jun¹²³,Xiang Haoyue¹²³^ORCID,Yang Hua¹²³^ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering, Central South University

2. Changsha

3. P. R. China

4. College of Chemistry and Materials Science, Guangxi Teachers Education University

5. Nanning

Abstract

Synergistic oxidation can do it! The precursor for matemone can be facilely prepared in 21% overall yield in 8 steps. The key step is the oxidative cyclization by utilizing CAN and TEMPO to install the quaternary centre.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NJ/C7NJ02246H

Reference43 articles.

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2. Synthesis and physical properties of various organic dyes derived from a single core skeleton, 1,2-dihydroindol-3-one

3. Synthesis of a new fluorescent small molecule probe and its use for in vivo lipid imaging

4. Indole Alkaloid Glycosides from the Aerial Parts of Strobilanthes cusia

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