A computational study of cell membrane damage and intracellular delivery in a cross-slot microchannel-Reference-Cited by-同舟云学术

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A computational study of cell membrane damage and intracellular delivery in a cross-slot microchannel

Published:2024 Issue:20 Volume:20 Page:4057-4071
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Lu Ruixin¹²^ORCID,Yu Peng³^ORCID,Sui Yi²^ORCID

Affiliation:

1. School of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China

2. School of Engineering and Materials Science, Queen Mary University of London, London E1 4NS, UK

3. Department of Mechanics and Aerospace Engineering, Southern University of Science and Technology, Shenzhen 518055, China

Abstract

The inertial effect increases the cell deformation and membrane damage in the channel cross-slot; however, the enhancement can be reversed by the cell membrane viscosity.

Funder

Royal Society

Queen Mary University of London

China Scholarship Council

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SM/D4SM00047A

Reference77 articles.

1. Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts

2. Nanoparticle-Mediated Delivery towards Advancing Plant Genetic Engineering

3. Opportunities and Challenges in the Delivery of mRNA-Based Vaccines

4. Microfluidic and Nanofluidic Intracellular Delivery

5. Engineering Efficient CAR‐T Cells via Electroactive Nanoinjection

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