A novel human arterial wall-on-a-chip to study endothelial inflammation and vascular smooth muscle cell migration in early atherosclerosis-Reference-Cited by-同舟云学术

A novel human arterial wall-on-a-chip to study endothelial inflammation and vascular smooth muscle cell migration in early atherosclerosis

Published:2021 Issue:12 Volume:21 Page:2359-2371
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Su Chengxun¹²³⁴²,Menon Nishanth Venugopal¹²³,Xu Xiaohan¹²³,Teo Yu Rong¹²³,Cao Huan⁵²³,Dalan Rinkoo⁶²³⁷⁸,Tay Chor Yong⁵²³^ORCID,Hou Han Wei¹²³⁶²^ORCID

Affiliation:

1. School of Mechanical and Aerospace Engineering

2. Nanyang Technological University, Singapore

3. Singapore

4. Interdisciplinary Graduate School

5. School of Materials Science & Engineering

6. Lee Kong Chian School of Medicine

7. Endocrinology Department

8. Tan Tock Seng Hospital, Singapore

Abstract

A novel microfluidic co-culture platform recapitulating the human arterial intima–media interface was developed for physiologically-relevant SMC migration studies.

Funder

National Medical Research Council

Ministry of Education - Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/LC/D1LC00131K

Reference61 articles.

1. WHO , World Health Organization. Cardiovascular diseases (CVDs) Fact Sheet , 2017

2. A Definition of Advanced Types of Atherosclerotic Lesions and a Histological Classification of Atherosclerosis

3. Atherosclerosis

4. Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype

5. Genetic Basis of Atherosclerosis: Insights From Mice and Humans

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