Iodine catalyzed one-pot four component synthesis of coumarinyl phosphoramidates via sequential addition of reactants-Reference-Cited by-同舟云学术

Iodine catalyzed one-pot four component synthesis of coumarinyl phosphoramidates via sequential addition of reactants

Published:2020 Issue:43 Volume:44 Page:18573-18578
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Imrankhan Mohammed¹²³⁴⁵,Shivashankar Kalegowda¹²³⁴⁵^ORCID

Affiliation:

1. P. G. Department of Chemistry

2. Central College Campus

3. Bangalore University

4. Bangalore

5. India

Abstract

An unprecedented synthetic route for the preparation of a library of novel coumarinyl phosphoramidate derivatives via iodine catalysed one-pot four component reactions of ethyl 4-bromo-3-oxo-alkanoate, sodium azide, trialkyl phosphites, and phenols in ethanol is reported.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/D0NJ04445H

Reference44 articles.

1. The diverse pharmacology and medicinal chemistry of phosphoramidates – a review

2. Direct-acting antiviral agents for hepatitis C: structural and mechanistic insights

3. Discovery of an Orally Active and Liver-Targeted Prodrug of 5-Fluoro-2′-Deoxyuridine for the Treatment of Hepatocellular Carcinoma