Two novel chiral tetranucleate copper-based complexes: syntheses, crystal structures, inhibition of angiogenesis and the growth of human breast cancer in vitro and in vivo-Reference-Cited by-同舟云学术

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Two novel chiral tetranucleate copper-based complexes: syntheses, crystal structures, inhibition of angiogenesis and the growth of human breast cancer in vitro and in vivo

Published:2021 Issue:41 Volume:50 Page:14684-14694
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Hou Xiao-Xiao¹,Ren Ya-Ping¹,Luo Zhao-Hui¹,Jiang Bing-Li¹,Lu Tian-Tian¹,Huang Fu-Ping²^ORCID,Qin Xiu-Ying¹²^ORCID

Affiliation:

1. College of Pharmacy, Department of Histology and Embryology, Guilin Medical University, Guangxi, Guilin, 541004, China

2. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmacy, Guangxi Normal University, Guangxi, Guilin, 541004, China

Abstract

Copper-based complex containing l-methioninol-derived Schiff-bases inhibited angiogenesis and induced apoptosis to resist breast cancer in vitro and in vivo.

Funder

Guangxi Normal University

Guilin Medical University

National Natural Science Foundation of China

Natural Science Foundation of Guangxi Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/DT/D1DT02033A

Reference41 articles.

1. Exploration of the medical periodic table: towards new targets

2. Genetic and molecular basis for copper toxicity

3. A Delicate Balance: Homeostatic Control of Copper Uptake and Distribution

4. Nitric Oxide Donors or Nitrite Counteract Copper-[dithiocarbamate]2-Mediated Tumor Cell Death and Inducible Nitric Oxide Synthase Down-Regulation: Possible Role of a Nitrosyl-Copper [Dithiocarbamate]2 Complex

5. Copper-Dependent Cytotoxicity of 8-Hydroxyquinoline Derivatives Correlates with Their Hydrophobicity and Does Not Require Caspase Activation

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3. Arene–Arene Coupled Disulfamethazines (or Sulfadiazine)-Phenanthroline-Metal(II) Complexes were Synthesized by In Situ Reactions and Inhibited the Growth and Development of Triple-Negative Breast Cancer through the Synergistic Effect of Antiangiogenesis, Anti-Inflammation, Pro-Apoptosis, and Cuproptosis;Journal of Medicinal Chemistry;2024-04-18

4. 8-hydroxyquinoline-N-oxide copper(II)- and zinc(II)-phenanthroline and bipyridine coordination compounds: Design, synthesis, structures, and antitumor evaluation;Journal of Inorganic Biochemistry;2024-02

5. Mononuclear copper(ii) complexes with polypyridyl ligands: synthesis, characterization, DNA interactions/cleavages and in vitro cytotoxicity towards human cancer cells;Dalton Transactions;2024

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