Nitric Oxide Donors or Nitrite Counteract Copper-[dithiocarbamate]2-Mediated Tumor Cell Death and Inducible Nitric Oxide Synthase Down-Regulation: Possible Role of a Nitrosyl-Copper [Dithiocarbamate]2 Complex-Reference-Cited by-同舟云学术

Nitric Oxide Donors or Nitrite Counteract Copper-[dithiocarbamate]2-Mediated Tumor Cell Death and Inducible Nitric Oxide Synthase Down-Regulation: Possible Role of a Nitrosyl-Copper [Dithiocarbamate]2 Complex

Published:2010-01-28 Issue:4 Volume:53 Page:1627-1635
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Rhenals Maricela Viola¹,Strasberg-Rieber Mary¹,Rieber Manuel¹

Affiliation:

1. Instituto Venezolano de Investigaciones Cientificas (IVIC), Centre for Microbiology & Cell Biology, Tumor Cell Biology Laboratory, Apartado 20632, Caracas 1020-A, Venezuela

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901314r

Reference27 articles.

1. Aberrant redox regulation in human metastatic melanoma cells compared to normal melanocytes

2. Disulfiram Facilitates Intracellular Cu Uptake and Induces Apoptosis in Human Melanoma Cells

3. Disulfiram, a Clinically Used Anti-Alcoholism Drug and Copper-Binding Agent, Induces Apoptotic Cell Death in Breast Cancer Cultures and Xenografts via Inhibition of the Proteasome Activity

4. Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells

5. Suppression of survival in human SKBR3 breast carcinoma in response to metal–chelator complexes is preferential for copper–dithiocarbamate

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