Metal complexes for the visualisation of amyloid peptides

Author:

Morfin Jean-François1,Lacerda Sara1ORCID,Geraldes Carlos F. G. C.23ORCID,Tóth Éva1ORCID

Affiliation:

1. Centre de Biophysique Moléculaire, CNRS, UPR 4301, Université d'Orléans, Rue Charles Sadron, 45071 Orléans Cedex 2, France

2. Department of Life Sciences and Coimbra Chemistry Centre, Faculty of Science and Technology, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal

3. CIBIT/ICNAS, University of Coimbra, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal

Abstract

Amyloid forms of different proteins are relevant biomarkers of pathologies like Alzheimer's disease or type 2 diabetes. Metal-based agents designed for the detection of such amyloid fibrils represent a rapidly growing field in molecular imaging.

Funder

Agence Nationale de la Recherche

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

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