Sulfur atom modification on thymine improves the specificity and sensitivity of DNA polymerization and detection-Reference-Cited by-同舟云学术

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Sulfur atom modification on thymine improves the specificity and sensitivity of DNA polymerization and detection

Published:2022 Issue:10 Volume:147 Page:2164-2169
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Li Yang¹^ORCID,Sun Wen¹,Luo Danyan²^ORCID,Yang Zhaoyi²,He Wei³,Huang Zhen¹²

Affiliation:

1. Key Laboratory of Bio-Resource and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan, China

2. SeNA Research Institute & Szostak-CDHT Large Nucleic Acids Institute, Chengdu, Sichuan, China

3. Sichuan International Travel Healthcare Center and Port Clinic of Chengdu Customs, Chengdu, Sichuan, China

Abstract

The incorporation of STTP can significantly reduce the non-specific amplification products in DNA polymerase reaction.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Sichuan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AN/D1AN02017J

Reference19 articles.

1. J.Ai , H.Zhang , T.Xu , J.Wu , M.Zhu , Y.Yu , H.Zhang , Z.Shen , Y.Li and X.Zhou , et al. , medRxiv, 2020

2. Antibody detection assays for COVID‐19 diagnosis: an early overview

3. Potential False-Negative Nucleic Acid Testing Results for Severe Acute Respiratory Syndrome Coronavirus 2 from Thermal Inactivation of Samples with Low Viral Loads

4. Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

5. The surprising pairing of 2-aminoimidazo[1,2-a][1,3,5]triazin-4-one, a component of an expanded DNA alphabet

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