Bioisosteric OH- to SH-replacement changes the antioxidant profile of ferulic acid

Author:

Chavarria Daniel12345ORCID,Fernandes Carlos12345ORCID,Silva Tiago12345ORCID,Garrido Jorge67895ORCID,Remião Fernando101112133ORCID,Oliveira Paulo J.1415165ORCID,Borges Fernanda12345ORCID

Affiliation:

1. CIQUP/Department of Chemistry and Biochemistry

2. Faculty of Sciences

3. University of Porto

4. 4169-007 Porto

5. Portugal

6. Department of Chemical Engineering

7. School of Engineering (ISEP)

8. Polytechnic of Porto

9. 4200-072 Porto

10. UCIBIO-REQUIMTE

11. Laboratory of Toxicology

12. Department of Biological Sciences

13. Faculty of Pharmacy

14. CNC - Center for Neuroscience and Cell Biology

15. University of Coimbra

16. Cantanhede

Abstract

A new ferulic acid-based thiophenol was synthesized and the differences in the antioxidant properties of the natural and the synthetic compounds were investigated.

Funder

Fundação para a Ciência e a Tecnologia

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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