Vibrational spectroscopic monitoring and biochemical analysis of pericellular matrix formation and maturation in a 3-dimensional chondrocyte culture model
Author:
Affiliation:
1. Institute of Science & Technology in Medicine
2. University of Keele
3. Stoke-on-Trent
4. UK
5. Diamond Light Source Ltd
6. Harwell Science and Innovation Campus
7. Oxfordshire
8. Cancer Centre
Abstract
PCA score of FTIR spectra in fingerprint region for cultured chondrocytes at day 7, 14 and 21 in HA hydrogel showing that the 3D culture drove chondrocytes (CY) to chondron-like (CN) structure dynamically.
Publisher
Royal Society of Chemistry (RSC)
Subject
Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/AN/C8AN01272E
Reference26 articles.
1. Chondrons and the Pericellular Matrix of Chondrocytes
2. The expanded collagen VI family: new chains and new questions
3. Tissue repair and the dynamics of the extracellular matrix
4. Retention of the native chondrocyte pericellular matrix results in significantly improved matrix production
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