Detection of lipid efflux from foam cell models using a label-free infrared method-Reference-Cited by-同舟云学术

Detection of lipid efflux from foam cell models using a label-free infrared method

Published:2022 Issue:23 Volume:147 Page:5372-5385
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Xie Bowen¹^ORCID,Njoroge Wanjiku¹,Dowling Lewis M.¹^ORCID,Sulé-Suso Josep¹²^ORCID,Cinque Gianfelice³^ORCID,Yang Ying¹^ORCID

Affiliation:

1. School of Pharmacy and Bioengineering, Keele University, Stoke-on-Trent, ST4 7QB, UK

2. Oncology Department, Cancer Centre, University Hospitals of North Midlands, Stoke-on-Trent, ST4 6QG, UK

3. MIRIAM beamline B22, Diamond Light Source, Harwell Science and Innovation Campus, Chilton-Didcot OX11 0DE, UK

Abstract

Synchrotron-based microFTIR spectroscopy was used to study the process of lipid efflux in a foam cell model. The anti-atherosclerotic drug, atorvastatin, removed low-density lipoprotein from the foam cells in a dose, and time dependent manner.

Funder

Diamond Light Source

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AN/D2AN01041K

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2. The Role of the Stem Cells Therapy in the Peripheral Artery Disease

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5. LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages

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