Piano-stool ruthenium(<scp>ii</scp>) complexes with maleimide and phosphine or phosphite ligands: synthesis and activity against normal and cancer cells-Reference-Cited by-同舟云学术

Piano-stool ruthenium(ii) complexes with maleimide and phosphine or phosphite ligands: synthesis and activity against normal and cancer cells

Published:2023 Issue:13 Volume:52 Page:4237-4250
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Juszczak Michał¹^ORCID,Das Sujoy²^ORCID,Kosińska Aneta²^ORCID,Rybarczyk-Pirek Agnieszka J.³^ORCID,Wzgarda-Raj Kinga³^ORCID,Tokarz Paulina¹^ORCID,Vasudevan Saranya⁴^ORCID,Chworos Arkadiusz⁴^ORCID,Woźniak Katarzyna¹^ORCID,Rudolf Bogna²^ORCID

Affiliation:

1. University of Lodz, Faculty of Biology and Environmental Protection, Department of Molecular Genetics, Pomorska 141/143, 90-236, Lodz, Poland

2. University of Lodz, Faculty of Chemistry, Department of Organic Chemistry, Tamka 12, 91-403 Lodz, Poland

3. University of Lodz, Faculty of Chemistry, Department of Physical Chemistry, Pomorska 163/165, 90-236 Lodz, Poland

4. Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland

Abstract

In these studies, we designed and investigated cyto- and genotoxic potential of five ruthenium cyclopentadienyl complexes bearing different phosphine and phosphite ligands.

Funder

Uniwersytet Łódzki

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/DT/D2DT04083B

Reference72 articles.

1. NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application

2. First-in-class ruthenium anticancer drug (KP1339/IT-139) induces an immunogenic cell death signature in colorectal spheroids in vitro

Ruthenium Complexes as Anticancer Agents: A Brief History and Perspectives