Somatostatin receptor-targeted organometallic iridium(iii) complexes as novel theranostic agents

Author:

Novohradsky Vojtech12345,Zamora Ana678910,Gandioso Albert678910,Brabec Viktor12345ORCID,Ruiz José1112131415ORCID,Marchán Vicente678910ORCID

Affiliation:

1. Institute of Biophysics

2. Academy of Sciences of the Czech Republic

3. v.v.i. Kralovopolska 135

4. 612 65 Brno

5. Czech Republic

6. Departament de Química Inorgànica i Orgànica

7. Secció de Química Orgànica

8. IBUB

9. Universitat de Barcelona

10. E-08028 Barcelona

11. Departamento de Química Inorgánica

12. Universidad de Murcia

13. and Institute for Bio-Health Research of Murcia (IMIB-Arrixaca)

14. E-30071 Murcia

15. Spain

Abstract

A novel somatostatin receptor-targeted anticancer agent based on the conjugation of a cyclometalated Ir(iii) complex to octreotide with potential for targeted theranostic applications.

Funder

Grantová Agentura České Republiky

Secretaría de Estado de Investigación, Desarrollo e Innovación

Fundación Séneca

European Cooperation in Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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