Pressure and cosolvent modulation of the catalytic activity of amyloid fibrils-Reference-Cited by-同舟云学术

Pressure and cosolvent modulation of the catalytic activity of amyloid fibrils

Published:2018 Issue:45 Volume:54 Page:5696-5699
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Jaworek Michel W.¹²³⁴⁵,Schuabb Vitor¹²³⁴⁵,Winter Roland¹²³⁴⁵^ORCID

Affiliation:

1. Faculty of Chemistry and Chemical Biology

2. TU Dortmund University

3. Otto-Hahn-Str. 4a

4. 44227 Dortmund

5. Germany

Abstract

We report on the effects of pressure and cosolvents on the catalytic activity of a designed amyloid fibril by applying a high-pressure stopped-flow methodology with rapid spectroscopic detection.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CC/C8CC00699G

Reference54 articles.

1. Protein Misfolding, Functional Amyloid, and Human Disease

2. Amyloid fibrils

3. Insights into protein misfolding and amyloidogenesis

4. Amyloid fibrils are the molecular trigger of inflammation in Parkinson's disease

5. Type 2 diabetes as a protein misfolding disease

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