Cascade bio-hydroxylation and dehalogenation for one-pot enantioselective synthesis of optically active β-halohydrins from halohydrocarbons-Reference-Cited by-同舟云学术

Cascade bio-hydroxylation and dehalogenation for one-pot enantioselective synthesis of optically active β-halohydrins from halohydrocarbons

Published:2019 Issue:16 Volume:21 Page:4324-4328
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Cui Hai-Bo¹²³⁴⁵,Xie Ling-Zhi¹²³⁴⁵,Wan Nan-Wei¹²³⁴⁵^ORCID,He Qing¹²³⁴⁵,Li Zhi⁶⁷⁸⁹,Chen Yong-Zheng¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province

2. Green Pharmaceuticals Engineering Research Center of Guizhou Province

3. School of Pharmacy

4. Zunyi Medical University

5. Zunyi

6. Department of Chemical and Biomolecular Engineering

7. National University of Singapore

8. Singapore 117585

9. Singapore

Abstract

A stereoselective hydroxylation and enantioselective dehalogenation cascade reaction was developed for the synthesis of optically active β-haloalcohols from halohydrocarbons.

Funder

National Natural Science Foundation of China

Guizhou Science and Technology Department

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/GC/C9GC01802F

Reference65 articles.

1. Enantioselective Nitrile Anion Cyclization to Substituted Pyrrolidines. A Highly Efficient Synthesis of (3S,4R)-N-tert-Butyl-4-Arylpyrrolidine-3-Carboxylic Acid

2. Pyridones as Highly Selective, Noncovalent Inhibitors of T790M Double Mutants of EGFR

3. Chemoenzymatic Synthesis of Luliconazole Mediated by Lipases

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