Controllability analysis of transcriptional regulatory networks reveals circular control patterns among transcription factors
Author:
Affiliation:
1. Novo Nordisk Foundation Center for Biosustainability
2. Department of Chemical and Biological Engineering
3. Chalmers University of Technology
4. SE-41296 Göteborg
5. Sweden
Abstract
Transcriptional regulation is the most committed type of regulation in living cells where transcription factors (TFs) control the expression of their target genes and TF expression is controlled by other TFs forming complex transcriptional regulatory networks that can be highly interconnected.
Publisher
Oxford University Press (OUP)
Subject
Biochemistry,Biophysics
Link
http://pubs.rsc.org/en/content/articlepdf/2015/IB/C4IB00247D
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