First stereoselective total synthesis of brevipolide M
Author:
Affiliation:
1. Natural Products Chemistry Division
2. CSIR-Indian Institute of Chemical Technology
3. Hyderabad 500 007
4. India
Abstract
The first stereoselective total synthesis of a cytotoxic brevipolide M, which shares a pyrone framework bearing a tetrahydrofuran moiety and a cinnamate group with the readily available (−)-DET, is described.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01438D
Reference34 articles.
1. Bioactive 5,6-Dihydro-α-pyrone Derivatives from Hyptis brevipes
2. Absolute Configuration and Conformational Analysis of Brevipolides, Bioactive 5,6-Dihydro-α-pyrones from Hyptis brevipes
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4. Three new compounds from the plant Lippia alva as inhibitors of chemokine receptor 5 (CCR5)
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