Hydroxysafflor yellow A triggered a fast-to-slow muscle fiber-type conversion via regulating FoxO1 in myocytes

Author:

Sun Yujie1,Wang Zhijun2,Nie Chenzhipeng1,Xue Lamei1,Wang Yu1,Liu Jinxin1ORCID,Fan Mingcong1,Zhang Duo3ORCID,He Ruikun4,Zhang Xuguang4,Qian Haifeng1,Chow Billy K. C.5,Li Yan1ORCID,Wang Li1ORCID

Affiliation:

1. State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China

2. COFCO Aerocean Oils & Grain Industrial Co. Ltd, Shawan, No. 1 West Park Road, West Urumqi Road, Shawan County, Tacheng District, Xinjiang Province 832100, China

3. Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia and Charlie Norwood VA Medical Center, Augusta, Georgia, USA

4. BYHEALTH Institute of Nutrition & Health, No. 3 Kehui 3rd Street, No. 99 Kexue Avenue Central, Huangpu District, Guangzhou 510663, China

5. School of Biological Sciences, University of Hong Kong, Hong Kong, China

Abstract

Hydroxysafflor yellow A (HSYA) is the main bioactive component of safflower and has been reported to have significant health-promoting abilities.

Funder

Six Talent Peaks Project in Jiangsu Province

Qinglan Project of Jiangsu Province of China

Young Elite Scientists Sponsorship Program by Tianjin

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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