Palladium-catalyzed synthesis of 2-alkenyl-3-arylindoles via a dual α-arylation strategy: formal synthesis of the antilipemic drug fluvastatin-Reference-Cited by-同舟云学术

Palladium-catalyzed synthesis of 2-alkenyl-3-arylindoles via a dual α-arylation strategy: formal synthesis of the antilipemic drug fluvastatin

Published:2015 Issue:45 Volume:13 Page:10995-11002
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kale Ajit Prabhakar¹²³⁴,Kumar Gangam Srikanth¹²³⁴,Kapur Manmohan¹²³⁴

Affiliation:

1. Department of Chemistry

2. Indian Institute of Science Education and Research Bhopal

3. Bhopal 462066

4. India

Abstract

A new approach has been developed for the synthesis of substituted 2-alkenyl-3-arylindoles utilizing a palladium-catalyzed dual α-arylation of TES-enol ethers of enones as the key step.

Funder

Science and Engineering Research Board

Council for Scientific and Industrial Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB01632K

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