Novel fast-acting pyrazole/pyridine-functionalized N-heterocyclic carbene silver complexes assembled with nanoparticles show enhanced safety and efficacy as anticancer therapeutics-Reference-Cited by-同舟云学术

Novel fast-acting pyrazole/pyridine-functionalized N-heterocyclic carbene silver complexes assembled with nanoparticles show enhanced safety and efficacy as anticancer therapeutics

Published:2020 Issue:8 Volume:49 Page:2505-2516
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Chen Chao¹²³⁴⁵^ORCID,Zhou Liqian¹²³⁴⁵,Xie Binbin⁶⁷⁴⁵⁸,Wang Yuchen¹²³⁴⁵,Ren Lulu⁶⁷⁴⁵⁸,Chen Xiaona¹²³⁴⁵,Cen Beini¹²³⁴⁵,Lv He⁹¹⁰¹¹¹²,Wang Hangxiang¹²³⁴⁵^ORCID

Affiliation:

1. The First Affiliated Hospital

2. Key Laboratory of Combined Multi-Organ Transplantation

3. Ministry of Public Health

4. School of Medicine

5. Zhejiang University

6. Department of Medical Oncology

7. Sir Run Run Shaw Hospital

8. Hangzhou

9. College of Life Sciences

10. Huzhou University

11. Huzhou

12. PR China

Abstract

Four multi-nuclear silver complexes with pyrazole/pyridine-functionalized NHC ligands were synthesized and characterized. The anticancer activity of these silver complexes was investigated both in vitro and in vivo.

Funder

National Natural Science Foundation of China

Huzhou University

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/DT/C9DT04751D

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