Switching between DNA binding modes with a photo- and redox-active DNA-targeting ligand-Reference-Cited by-同舟云学术

Switching between DNA binding modes with a photo- and redox-active DNA-targeting ligand

Published:2023 Issue:9 Volume:21 Page:1958-1966
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Dohmen Christoph¹,Ihmels Heiko¹^ORCID

Affiliation:

1. Department of Chemistry and Biology, University of Siegen, and Center of Micro- and Nanochemistry and (Bio)Technology (Cμ), Adolf-Reichwein-Str. 2, 57068 Siegen, Germany

Abstract

The combination of a photochromic benzo[b]quinolizinium and a redox-active disulfide linker enables the control of DNA-binding properties by shifting between three different binding modes.

Funder

Universität Siegen

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00013C

Reference57 articles.

1. Cancer Statistics, 2021

2. Discovery of DNA-Targeting HDAC Inhibitors with Potent Antitumor Efficacy In Vivo That Trigger Antitumor Immunity

3. Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components

4. An overview of recent advances in duplex DNA recognition by small molecules

5. Nanomedicine-enabled chemotherapy-based synergetic cancer treatments

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