Transition-metal-free synthesis of 4-amino isoquinolin-1(2<i>H</i>)-ones <i>via</i> a tandem reaction of arynes and oxazoles-Reference-Cited by-同舟云学术

Transition-metal-free synthesis of 4-amino isoquinolin-1(2H)-ones via a tandem reaction of arynes and oxazoles

Published:2022 Issue:6 Volume:9 Page:1550-1555
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Liu Shaojun¹,Xie Pei¹,Wu Leifang²,Zhao Jixing²,Cai Zhihua¹^ORCID,He Lin¹^ORCID

Affiliation:

1. Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering, Shihezi University, Xinjiang Uygur Autonomous Region 832000, People's Republic of China

2. Analysis and Testing Center of Shihezi University, Xinjiang Uygur Autonomous Region, 832000, China

Abstract

A facile and transition-metal-free method for the synthesis of 4-amino isoquinolin-1(2H)-ones has been developed.

Funder

Shihezi University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D1QO01666K

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2. Second Generation Analogues of the Cancer Drug Clinical Candidate Tipifarnib for Anti-Chagas Disease Drug Discovery

3. Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (2)

4. One-pot tandem Hurtley–retro-Claisen–cyclisation reactions in the synthesis of 3-substituted analogues of 5-aminoisoquinolin-1-one (5-AIQ), a water-soluble inhibitor of PARPs

5. The synthesis of 2,3,6-trisubstituted 1-oxo-1,2-dihydroisoquinolines as potent CRTh 2 antagonists

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