Palladium-catalyzed cascade cyclization for the construction of spiro-N,O-acetals

Author:

Cheng Jiashun123,Chen Pinhong123,Liu Guosheng123

Affiliation:

1. State Key Laboratory of Organometallic Chemistry

2. Shanghai Institute of Organic Chemistry

3. Shanghai, China

Abstract

A facile Pd-catalyzed cascade cyclization of N-alkenylamine and pyruvic acids has been developed to construct spiro-N,O-acetals efficiently.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference37 articles.

1. R. F. Heck , Palladium Reagents in Organic Synthesis , Academic , New York , 1985

2. A. Ricci , Modern Amination Methods , Wiley-VCH , Weinheim , 2000

3. K. C. Nicolaou and E. J.Sorensen , Classics in Total Synthesis: Targets, Strategies, Methods , Wiley-VCH , Weinheim , 1996

4. E. Negishi , Handbook of Organopalladium Chemistry for Organic Synthesis , John Wiley & Sons , New York , 2002

5. B. M. Trost and I.Fleming , Comprehensive Organic Synthesis , Pergamon , Oxford , 1991

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