Electrophilic activation of nitroalkanes in efficient synthesis of 1,3,4-oxadiazoles
Author:
Affiliation:
1. Department of Chemistry
2. North Caucasus Federal University
3. Stavropol 355009
4. Russian Federation
5. Department of General Practice Dentistry and Child Dentistry
6. Stavropol State Medical University
7. Stavropol 355017
Abstract
A novel methodology for chemoselective preparation of non-symmetric 1,3,4-oxadiazoles via PPA-assisted activation of nitroalkanes towards nucleophilic attack with acylhydrazides is developed.
Funder
Russian Foundation for Basic Research
Ministry of Education and Science of the Russian Federation
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA00976K
Reference35 articles.
1. 1,3,4-Oxadiazole: A Biologically Active Scaffold
2. Synthesis of a newC2-symmetric chiral catalyst and its application in the catalytic asymmetric borane reduction of prochiral ketones
3. Design of a Semirigid Molecule as a Selective Fluorescent Chemosensor for Recognition of Cd(II)
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