Expeditious access of chromone analogues via a Michael addition-driven multicomponent reaction-Reference-Cited by-同舟云学术

Expeditious access of chromone analogues via a Michael addition-driven multicomponent reaction

Published:2020 Issue:8 Volume:7 Page:987-992
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Lei Jie¹²³⁴⁵,Li Yong¹²³⁴⁵,He Liu-Jun¹²³⁴⁵,Luo Ya-Fei¹²³⁴⁵,Tang Dian-Yong¹²³⁴⁵^ORCID,Yan Wei⁶¹⁷⁸⁹,Lin Hui-Kuan¹⁰¹¹¹²¹³⁹,Li Hong-yu⁶¹⁷⁸⁹,Chen Zhong-Zhu¹²³⁴⁵,Xu Zhi-Gang¹²³⁴⁵^ORCID

Affiliation:

1. College of Pharmacy

2. National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics

3. Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine

4. Chongqing University of Arts and Sciences

5. Chongqing 402160

6. Department of Pharmaceutical Sciences

7. University of Arkansas for Medical Sciences

8. Little Rock

9. USA

10. Department of Cancer Biology

11. Wake Forest School of Medicine

12. Medical Center Boulevard

13. Winston-Salem

Abstract

A Michael addition-driven four-component reaction (4-CR) with four Ugi inputs was developed and utilized for the synthesis of chromone derivatives and tetrazole substituted chromones under mild reaction conditions.

Funder

Chongqing Municipal Education Commission

Natural Science Foundation of Chongqing

Chongqing University of Arts and Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO00145G

Reference55 articles.

1. Natural Product-like Combinatorial Libraries Based on Privileged Structures. 1. General Principles and Solid-Phase Synthesis of Benzopyrans