Synthesis and cytotoxicity of novel simplified eleutherobin analogues as potential antitumour agents

Author:

Sosonyuk Sergey E.1234,Peshich Anita1234,Tutushkina Anastasia V.1234,Khlevin Dmitry A.1234,Lozinskaya Natalia A.12345ORCID,Gracheva Yulia A.1234,Glazunova Valeria A.634,Osolodkin Dmitry I.12347ORCID,Semenova Marina N.8934,Semenov Victor V.10934,Palyulin Vladimir A.12345,Proskurnina Marina V.12345,Shtil Alexander A.12346,Zefirov Nikolay S.12345

Affiliation:

1. Department of Chemistry

2. Lomonosov Moscow State University

3. Moscow

4. Russia

5. Institute of Physiologically Active Compounds

6. Blokhin National Medical Center of Oncology

7. FSBSI “Chumakov FSC R&D IBP RAS”

8. Institute of Developmental Biology

9. Russian Academy of Sciences

10. Zelinsky Institute of Organic Chemistry

Abstract

Synthesis of title compounds based on adamantane and 8-oxabicyclo[3.2.1]octane scaffolds and evaluation of their biological activity.

Funder

Russian Foundation for Basic Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Reactions of 1,3-dihaloadamantanes with nitric acid;Журнал органической химии;2023-03-15

2. Reaction of 1,3-Dihaloadamantanes with Nitric Acid;Russian Journal of Organic Chemistry;2023-03

3. Deep Learning Promotes the Screening of Natural Products with Potential Microtubule Inhibition Activity;ACS Omega;2022-08-05

4. Marine natural products;Natural Product Reports;2021

5. Synthesis and cytotoxic activity of isocembrol and its hydroxy derivatives;Russian Chemical Bulletin;2020-10

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