Affiliation:
1. Samara State Technical University
Abstract
The reaction of 1,3-dibromoadamantanes with fuming nitric acid gave the mixture of 2-oxaadamantane derivatives. In the same conditions 1,3-diiodoadamantanes gave the corresponding 1,3-dinitroxyadamantanes. A preparative method for the synthesis of 5,7-dimethyl-3-bromomethyl-1-hydroxy-2-oxaadamantan-1-ol from 5,7-dimethyl-1,3-dibromoadamantane was developed. The obtained compounds can be used in the directed synthesis of substances with high molecular complexity for studying of biological activity.
Publisher
The Russian Academy of Sciences