Mannosylated adamantane-containing desmuramyl peptide recognition by the NOD2 receptor: a molecular dynamics study-Reference-Cited by-同舟云学术

Mannosylated adamantane-containing desmuramyl peptide recognition by the NOD2 receptor: a molecular dynamics study

Published:2021 Issue:32 Volume:19 Page:7001-7012
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Maršavelski Aleksandra¹^ORCID,Paurević Marija²^ORCID,Ribić Rosana³^ORCID

Affiliation:

1. Department of Chemistry, Faculty of Science, University of Zagreb, HR-10000 Zagreb, Croatia

2. Department of Chemistry, Josip Juraj Strossmayer University Osijek, HR-31000 Osijek, Croatia

3. University Center Varaždin, University North, HR-42000 Varaždin, Croatia

Abstract

The dipeptide isoGln moiety of ManAdDMP significantly contributes to the binding to the NOD2 receptor. Loops 2 and 7 are important for ligand recognition and could be useful for further investigation of NOD2 activation/inhibition.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00679G

Reference47 articles.

1. Pattern Recognition Receptors and Inflammation

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5. NOD1 and NOD2 in inflammatory and infectious diseases

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