Novel fatty chain-modified GLP-1R G-protein biased agonist exerts prolonged anti-diabetic effects through targeting receptor binding sites-Reference-Cited by-同舟云学术

Novel fatty chain-modified GLP-1R G-protein biased agonist exerts prolonged anti-diabetic effects through targeting receptor binding sites

Author:

Wang Maorong¹²³⁴⁵,Yao Ping¹⁶⁷⁸,Gao Minpeng⁹¹⁰¹¹,Jin Jian¹²¹³¹¹,Yu Yerong¹²³⁴⁵

Affiliation:

1. Department of Endocrinology

2. West China Hospital

3. Sichuan University

4. Chengdu

5. China 610041

6. Affiliated Hospital of Hubei University for Nationalities

7. Enshi 445000

8. China

9. China Pharmaceutical University

10. Nanjing

11. P. R. China

12. Jiangnan University

13. Wuxi

Abstract

An autocrine selected GLP-1R agonist was modified via site-specific fatty chain and exerted prolonged antidiabetic effects.

Funder

Ministry of Science and Technology of the People's Republic of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

Reference34 articles.

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