Selection of aptamers specific for glycated hemoglobin and total hemoglobin using on-chip SELEX-Reference-Cited by-同舟云学术

Selection of aptamers specific for glycated hemoglobin and total hemoglobin using on-chip SELEX

Published:2015 Issue:2 Volume:15 Page:486-494
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Lin Hsin-I¹²³⁴,Wu Ching-Chu⁵⁶⁷⁸,Yang Ching-Hsuan¹²³⁴,Chang Ko-Wei⁵⁶⁷⁸,Lee Gwo-Bin⁵⁶⁷⁸⁹,Shiesh Shu-Chu¹²³⁴

Affiliation:

1. Department of Medical Laboratory Science and Biotechnology

2. National Cheng Kung University

3. Tainan

4. Taiwan 701

5. Department of Power Mechanical Engineering

6. National Tsing Hua University

7. Hsinchu

8. Taiwan 30013

9. Institute of Biomedical Engineering

Abstract

Selection of blood glycated hemoglobin (HbA1c)- and total hemoglobin (Hb)-specific single-stranded DNA aptamers was performed on a microfluidic chip to continuously and automatically carry out multiple rounds of systematic evolution of ligands by exponential enrichment (SELEX) processes.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2015/LC/C4LC01124D

Reference32 articles.

1. Haemoglobin A1c in the diagnosis and monitoring of diabetes mellitus

2. A New Look at Screening and Diagnosing Diabetes Mellitus

3. Implications of Using Hemoglobin A1C for Diagnosing Diabetes Mellitus

4. The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus

5. Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes

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