Associations between environmental characteristics, high-resolution indoor microbiome, metabolome and allergic and non-allergic rhinitis symptoms for junior high school students

Author:

Fu Xi1,Du Bingqian1,Meng Yi234,Li Yanling234,Zhu Xunhua234,Ou Zheyuan234,Zhang Mei234,Wen Huarong5,Ma'pol Aminnuddin6,Hashim Jamal Hisham7,Hashim Zailina8,Wieslander Gunilla9,Chen Qingmei234,Jiang Jun234,Wang Juan9,Norbäck Dan9,Xia Yun1,Chen Qingsong1,Sun Yu234ORCID

Affiliation:

1. Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, 510006, PR China

2. Guangdong Provincial Key Laboratory of Protein Function and Regulation in Agricultural Organisms, College of Life Sciences, South China Agricultural University, Guangzhou, Guangdong, 510642, PR China

3. Key Laboratory of Zoonosis of Ministry of Agriculture and Rural Affairs, South China Agricultural University, Guangzhou, Guangdong, 510642, PR China

4. Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University, Guangzhou, Guangdong, 510642, China

5. Baling Health Center, Dangyang, Hubei, 444100, PR China

6. Gombak District Health Office, Ministry of Health, Batu Caves, Selangor Darul Ehsan, Malaysia

7. Universiti Selangor, Shah Alam, Selangor, Malaysia

8. Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, UPM, Serdang, Selangor, Malaysia

9. Occupational and Environmental Medicine, Department of Medical Science, University Hospital, Uppsala University, 75237 Uppsala, Sweden

Abstract

Bacteria Brasilonema bromeliae and Aeromonas enteropelogenes and the metabolite pipecolic acid were protectively associated with both allergic and non-allergic rhinitis symptoms. Pipecolic acid was highly co-occurrent with B. bromeliae.

Funder

Natural Science Foundation of Guangdong Province

Guangzhou Municipal Science and Technology Project

Publisher

Royal Society of Chemistry (RSC)

Subject

Management, Monitoring, Policy and Law,Public Health, Environmental and Occupational Health,Environmental Chemistry,General Medicine

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